The NALM-6 mannequin, a worthwhile instrument in preclinical leukemia analysis, entails the implantation of human acute lymphoblastic leukemia cells into immunodeficient mice. This creates a residing system that mirrors the development and response to remedy seen in human leukemia, permitting researchers to check the illness and take a look at potential remedies in a extra managed setting.
This mannequin’s improvement offered researchers with a crucial platform for testing new therapies and finding out leukemia improvement. It permits for detailed evaluation of illness development, drug resistance mechanisms, and the interplay between leukemia cells and the microenvironment. The power to check potential remedies in vivo earlier than scientific trials gives a extra environment friendly and moral strategy to drug improvement, contributing to the development of leukemia remedy.
